Metabolic syndrome (METS) and diabetes mellitus (DM) were significant comorbid conditions in lacunar stroke patients and they were associated with stroke recurrence, according to a study of 3,020 patients with lacunar strokes.
25% of patients had METS only, 6% had DM only, 32% had both conditions, and 37% had neither.
Over a median 3.8 years of follow-up, there were 274 recurrent strokes and 74 myocardial infarctions (MIs).
Among 240 recurrent ischemic strokes, 56% were lacunar.
The hazard ratios for any recurrent stroke or lacunar stroke were significantly higher for those with concurrent METS and DM vs those who had neither.
Risk of incident MI was higher in patients with DM or concurrent DM and METS
Zhu S, McClure LA, Lau H, et al.
Recurrent vascular events in lacunar stroke patients with metabolic syndrome and/or diabetes.
August 21, 2015.